Surgical technique: establishing a pre-clinical large animal model to test aortic valve leaflet substitute.
نویسندگان
چکیده
To overcome current limitations of valve substitutes and tissue substitutes the technology of tissue engineering (TE) continues to offer new perspectives in congenital cardiac surgery. We report our experiences and results implanting a decellularized TE patch in nine sheep in orthotropic position as aortic valve leaflet substitute. Establishing the animal model, feasibility, cardiopulmonary bypass issues and operative technique are highlighted.
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ورودعنوان ژورنال:
- Journal of thoracic disease
دوره 8 12 شماره
صفحات -
تاریخ انتشار 2016